Lost Universe: Nina Mercury

 Nina Mercury is a member of  the Interstellar Police Force working as a secretary under Raily Claymore.  She will often spill coffee on Raily and has a knack for disabling machines with a touch.

His and Her Circumstances (Kare Kano): Tsubasa Shibahime

 Tsubasa is a tomboyish high school girl who looks younger than she actually is and often acts spoiled.  She was held back a year after a bad skateboarding accident left her hospitalized for a long time.  Her mother died during childbirth and is overprotective of her father and is opposed of his marriage to Yumi.  After a while Tsubasa does see that she is being selfish and becomes supportive of the union and seems to have a happy life with her new step-mother and step-brother.  In fact after graduation she marries her step-brother Kazuma Ikeda.