Debuting in the show's second season, Karai eventually became one of the series' main non-turtle characters. A woman torn between honor and family, she appears both as an ally and enemy to the turtles,
a dichotomy that plays a part in most of her appearances. Her
allegiance varied throughout the series: first being an anti-hero (or
anti-villain) during seasons 2-3,then villain in seasons 4 and 5 and
finally became heroic near the end of season 5 and in later episodes.
Some more of Karai can be found in these previous tributes to the character here:
http://animefeet.blogspot.com/2009/08/villainess-takeover-karai.html
http://animefeet.blogspot.com/2008/09/karai-bonus.html